2014年12月19日星期五

The reason edema renal syndrome

Current kidney medical profession, for renal syndrome edema main reasons there are two views, the traditional "filling without feet" hypothesis that urinary albumin since lost cause hypoalbuminemia, since intravascular fluid into the interstitial. Stimulate the kidneys to reduce plasma volume of water and sodium retention. Final plasma colloid osmotic pressure and interstitial hydrostatic equilibrium, edema and stability.
So reducing plasma volume is the key to stimulate the kidneys Shuinazhuliu. Clinically also observed in some patients with renal syndrome reduces plasma volume, plasma volume expansion after hypotension and reduced cardiac output corrected; arterial capacity is not increased foot mark fluids such as plasma renin activity, aldosterone and catecholamine levels. After the expansion, such as albumin or flooding injection therapy can increase GFR and filtration fractional excretion of sodium.
Patients with renal comprehensive adrenergic nerve activity increased perhaps the most early signs. However, in recent years, as some patients exhibit, edema of renal syndrome in patients with normal or elevated blood volume, and even high blood pressure and plasma renin activity decreased plasma albumin not necessarily reduce edema. Kidney patients often have a comprehensive filtration fraction decreased, while arterial filling feet should not be increased filtration fraction, so the hypothesis put forward over filling. The first hypothesis is that the kidney retention of water and sodium, and the reason has nothing to do with the body. Renal sodium retention in plasma volume expansion, plasma volume filling excessive leakage to interstitial edema formation. Hypoalbuminemia accelerate edema formation.
Why renal comprehensive patient can have two completely different capacity and fluid parameters, this may be a completely different reason these types of kidney disease patients, GFR, systemic disease, hypoalbuminemia extent and application of diuretics .
In short, when the distal renal syndrome renal tissue is the primary site of sodium reabsorption, in some cases, not the same and based on sodium retention state, may also participate in the proximal tubule sodium reabsorption kidney disease type.

When renal comprehensive patient showed edema, renal comprehensive medicine dialectical treatment is essential. My website belongs nationwide kidney specialist kidney hospital kidney survey He Ruiqi hospital director said that the Board has both the root causes of renal comprehensive treatment advantages, to achieve the purpose of cure does not rebound.