Experts answer Shijiazhuang kidney disease hospital of kidney failure is
caused by many reasons, such as: nephrotoxicity and renal ischemia.
First, renal toxicity to the kidney toxic substances, such as carbon
tetrachloride drugs, mercury agents, bismuth, dichloro-sulfamethoxazole
(dichlorphenamide); polymyxin antibiotics, vancomycin, kanamycin , and iodinated
contrast, methoxyflurane anesthetics; biological toxins such as snake venom, bee
venom, etc., can under certain conditions cause acute tubular necrosis.
Second, severe renal ischemia and renal ischemia such as severe trauma,
extensive burns, major surgery, massive blood loss, sepsis, obstetric
hemorrhage, dehydration and electrolyte imbalance, particularly with shock who
are easily lead to acute tubular necrosis. Or various chronic nephritis,
long-term hypertension, diabetes, glomerular filtration rate caused by extremely
reduced. Generating mechanism may be due to various causes renal tubular
preceding ischemia or intoxication, renal tubular epithelial cell injury occurs,
so the proximal tubule reabsorption of sodium reduction, so that the original
urine sodium, water increased. When it flows through the macula densa of the
distal convoluted tubule, juxtaglomerular stimulate the release of renin,
angiotensin Ⅱ so that increased activity in the kidney, causing contraction of
glomerular small artery spasm, leading to glomerular especially outer cortical
blood flow decreased glomerular, filtration rate is extremely reduced.
Detoxification function of the kidney appears to reduce elevated serum
creatinine lead. If you have additional questions online consultation
Shijiazhuang kidney disease hospital doctor. We will provide free help.
